Detail publikace

BenchStab: A tool for automated querying of web-based stability predictors

VELECKÝ, J. BEREZNÝ, M. MUSIL, M. MAZURENKO, S. BEDNÁŘ, D. DAMBORSKÝ, J.

Originální název

BenchStab: A tool for automated querying of web-based stability predictors

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

Protein design requires information about how mutations affect protein stability. Many web-based predictors are available for this purpose, yet comparing them or using them en masse is difficult. Here, we present BenchStab, a console tool/Python package for easy and quick execution of 19 predictors and result collection on a list of mutants. Moreover, the tool is easily extensible with additional predictors. We created an independent dataset derived from the FireProtDB and evaluated 24 different prediction methods.

Klíčová slova

prediction of stability, protein stability, web-tools, benchmarking

Autoři

VELECKÝ, J.; BEREZNÝ, M.; MUSIL, M.; MAZURENKO, S.; BEDNÁŘ, D.; DAMBORSKÝ, J.

Vydáno

15. 9. 2024

Nakladatel

Oxford University Press

ISSN

1367-4803

Periodikum

BIOINFORMATICS

Ročník

40

Číslo

9

Stát

Spojené království Velké Británie a Severního Irska

Strany od

1

Strany do

8

Strany počet

8

URL

https://academic.oup.com/bioinformatics/article/40/9/btae553/7755040

Plný text v Digitální knihovně

http://hdl.handle.net/11012/252347

BibTex

@article{BUT189729,
  author="Jan {Velecký} and Matej {Berezný} and Miloš {Musil} and Jiří {Damborský} and David {Bednář} and Stanislav {Mazurenko}",
  title="BenchStab: A tool for automated querying of web-based stability predictors",
  journal="BIOINFORMATICS",
  year="2024",
  volume="40",
  number="9",
  pages="1--8",
  doi="10.1093/bioinformatics/btae553",
  issn="1367-4803",
  url="https://academic.oup.com/bioinformatics/article/40/9/btae553/7755040"
}

Odpovědnost: Ing. Marek Strakoš